For the first time analyzed the association of pathogenicity genes and species of enterococci isolated from different biotopes of the people living in the city of Irkutsk. Established that on two medically significant species of enterococci (E. faecalis and E. faecium) prevails E. faecium. Greater potential for pathogenicity is concentrated on E. faecalis. Of the analyzed genes of pathogenicity, encoding proteins of adhesion (asa1) and cytolysin (cylA), in the studied sample of cultures, microbiological typed the genus Enterococcus, usually a fixed first. Compatibility of the species with other species of enterococci unidentifiable us for each of the studied biotopes (intestinal, vaginal, nasopharyngeal) had original differences with the fullest spectrum of species and their associations in the intestinal. Investigated genes of pathogenicity met in samples from a man's part of sample is more often. Display of studied genes of pathogenicity didn't depend on age.