List of issues > Series «Biology. Ecology». 2010. Vol. 2
Evaluation of MXR activity in freshwater amphipod detected by intensity of rhodamine B efflux
Author(s)
M. A. Timoveyev, Zh. M. Shatilina, V.V. Pavlichenko, D. S. Bedulina, M. V. Protopopova, D. V. Axenov-Gribanov, E. A. Sapozhnikova
Abstract
The aim of present study was an evaluation of possibility to use fluorometric method for multixenobiotic
resistance mechanism’s (MXR) activity detection in Baikalian organisms. Eulimnogammarus cyaneus (Dyb.),
an endemic amphipods species, was used. MXR activity in control condition and by cadmium chloride exposure was
evaluated. It was shown, that activation of MXR was induced by fluorometric substance in studied amphipods. Exposure
of amphipods to cadmium chloride led to inhibit of MXR activity. It was concluded that described method of
evaluation of MXR activity can be used for ecotoxicological studies.
Keywords
multixenobiotic resistance mechanism’s (MXR), amphipods, Baikal, cadmium chloride, rhodamine B
UDC
574.5 574.2 574.24