The status of lipid peroxidation based on malondialdehyde and diene conjugates in blood plasma of European rabbit grown at different feeding options, as well as state of the enzymatic antioxidant system superoxide dismutase and catalase were investigated. The dependence of lipid peroxidation, as well as changes in the concentration of antioxidant enzymes on type of food is demonstrated. The ability of food containing antioxidant substances of natural origin, to normalize the balance of antioxidant protection and to reduce oxidative stress is revealed.