The influence of temperature on growth rate of some basidiomycetes from Baikal region: Hericium coralloides (Fr.) Pers, Hypsizygus ulmarius (Bull.) Redhead and Inonotus rheades (Pers.) Bondartsev & Singer was examined. The optimum temperature for growth of fungi 20 °C. Тotal antioxidant capacity (ТAС) of extracts from basidiomycetes mycelia cultured at different temperatures (15, 20, 30 °C) has been defined. The content of the standard antioxidant calculated per gram of extractives by phosphomolybdic method for P. Preito et al. The maximum antioxidant potential H. coralloides, I. rheades and H. ulmarius is observed at 15 °C and is 195,8 153,6 132,9 mg/g, respectively. During operation it was established, the lower cultivation temperature gives the higher antioxidant activity.