New experimental data on sanitary-and-environmental properties of the soil cover in the town of Cheremkhovo and adjacent areas under the conditions of Siberia were obtained. High concentrations of polluting chemicals, including heavy metals, were identified. The values of acid-alkali conditions of soils range from 5.6 to 8.1 pH. The level of saprophytic microflora is shown, which varies widely (from 0.054 to 10.3 mln CFU/g) depending on the study area. A qualitative characteristic of the main taxonomic groups of microorganisms is given. An assessment of the sanitary state of the soil cover according to the established standards revealed that it is close to an epidemically dangerous one. Biological activity of soils is relatively not high and is twice lower than the control variants.